novaSMART

PROBIOTIC DRAGEES TO SUPPORT THE MOOD AND COGNITIVE FUNCTINALITY OVER THE GUT-BRAIN AXIS

nova SMART is a food supplement with probiotics enclosed in tasty coffee dragée

• Exclusive probiotics combination for a complete regulation of the gut-brain axis
• Synergic combination studied
• Tasty dragées made by a unique coffee matrix, patented (PCT)
• There is no chocolate!
• 20 dragées provide the natural caffeine of a single espresso
• Label registered; Free-sale certificate available

Scientific Data

The selected probiotics have been studied to evaluate their effect on the modulation of the gut-brain axis. The model used is valid for in vitro studies on depression and anxiety and allows to evaluate:

• Cytotoxicity and cell-protection against oxidative damages
• Inflammatory picture
• Biomarkers for anxiety
• Biomarkers for neurodegeneration
• Interleukins involved in anxiety and depression
• Analysis of apoptotic activity
• Analysis of the production of neurotrophic factors
• Analysis of the expression of proteins implicated in brain plasticity
• Analysis of membrane potential and mitochondrial metabolism
• Quantification of glutamate, homocysteine and serotonin levels

The combination of B. bifidum, B. longum and L. paracasei was the one achieving the best cumulative scores in all the model compartments.

The novaSMART combo is able to exert a greater effect on the Gut-Brain model compared to other tested agents (p<0. 05), thus resulting in better support for mood regulation and having a greater influence on neuronal environment.

Indications

20 dragées provide the natural caffeine of a single espresso

Ingredients

B. bifidum + B. longum + L. paracasei in a tasty 100% PURE COFFEE DRAGÉES